Cookies

We use cookies to ensure that we give you the best experience on our website. By continuing to browse this repository, you give consent for essential cookies to be used. You can read more about our Privacy and Cookie Policy.


Durham e-Theses
You are in:

New studies in aromatic chloromethylation

Eglington, Michael (1992) New studies in aromatic chloromethylation. Masters thesis, Durham University.

[img]
Preview
PDF
883Kb

Abstract

Chloromethylation reactions of anisole, cumene and trifluoromethylbenzene have been examined using the reagents formaldehyde and hydrogen chloride, in the presence of an extensive range of catalysts. Reaction conditions and choice of catalyst have been optimised to obtain a high ratio of chloromethylated product: diarylmethane product. For anisole this requires the use of titanium tetrachloride as catalyst at O-5ºC; for cumene, zinc chloride as catalyst at 42-48ºC gives the best results. Trifluoromethylbenzene could not be chloromethylated using the HCI/CH(_2)O/ catalyst system. Other alkoxybenzene substrates and chloromethylating reagents have been briefly studied.

Item Type:Thesis (Masters)
Award:Master of Science
Thesis Date:1992
Copyright:Copyright of this thesis is held by the author
Deposited On:18 Dec 2012 12:00

Social bookmarking: del.icio.usConnoteaBibSonomyCiteULikeFacebookTwitter